Chinese study: More than half of 1,000 new Crown patients discharged from hospital still have symptoms after 2 years

The study showed that 55% of patients had at least one sequela 2 years after disease onset. (courtesy of cctv news)


A Chinese research team visiting Wuhan Jinyintan Hospital in a study of patients diagnosed with new crowns showed that 55% of patients developed at least one sequela 2 years after disease onset. among them, fatigue ormuscleAsthenia is the symptom with the highest proportion, up to 30%, and also occurs in patients withjointSymptoms such as pain, palpitations, dizziness and headache. Patients were more likely to experience anxiety and depression than non-patients, with 12% having symptoms of anxiety or depression.

The team reports the development of COVID-19 hospitalized survivors of varying severity within 2 years after acute infection.MedicineThe team, led by Professor Wang Jianwei from Peking Union Medical College of the Academy of Sciences, completed the work.


The study noted that between January 7, 2020 and May 29, 2020, a total of 2,469 new Crown patients were discharged from Wuhan Jinyintan Hospital, of whom 1,119 received face-to-face interviews 2 years after infection.

The study showed that 68% of patients had at least one sequela 6 months after initial onset; After 2 years, that rate dropped to 55%, with fatigue or muscle weakness being the most common symptom, up from 52 at 6 months. Dropped to 30% in two years.

Two years after onset, patients had generally poorer health than the general population, with 31% experiencing fatigue or muscle weakness, 31% difficulty sleeping, and patients experiencing other symptoms including joint pain, palpitations, dizziness, and headache. were more likely to experience

In the quality of life survey, people with COVID-19 were more likely to have pain or discomfort, anxiety or depression than people without COVID-19. However, these quality of life issues also continued to improve, particularly in relation to anxiety or depression, where the proportion of individuals with symptoms of anxiety or depression decreased from 23% at 6 months to 12% at 2 years.

Notably, at the 2-year follow-up, the burden of restrictive ventilatory disorders was significantly higher on critically ill patients and diffuse lung injury than controls.

Furthermore, regardless of the severity of the initial disease, 89% of patients returned to their previous jobs after 2 years.

Despite the severity of the initial illness, the physical and mental health of patients who were discharged from COVID-19 improved over time, with most returning to work within 2 years, the team concluded. However, the burden of symptomatic sequelae remains significantly higher, and the health outcomes of these patients are significantly lower after 2 years than in the general population.

Cao Bin said that the findings suggest that for a certain percentage of COVID-19 hospitalized survivors, it takes more than 2 years to fully recover from COVID-19, Although they may have cleared the initial infection. He emphasized that the ongoing follow-up of COVID-19 survivors, especially those with long-term symptoms of COVID-19 (coronavirus long-term symptoms), is important for understanding the longer course of the disease, and planning recovery plans. Further search. Recovery is also important.

Cao Bin reminded that there is a need to continue supporting a larger proportion of patients and understanding how vaccines, emerging treatments and new coronavirus variants affect long-term health outcomes.

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